- June 22, 2022
- Posted by: daslore
- Category: Uncategorized
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Solucionario Antenas
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Immunomodulatory activity of antibody-Fc-coupled dipeptidyl peptidase III in vitro.
Dipeptidyl peptidase III (DPP III) is a homolog of CD26, which is expressed by several cell types, including immune cells. However, its function is not yet fully understood. Here, we show that expression of DPP III is up-regulated on T cells following an immune response in vivo. Moreover, DPP III is constitutively expressed in human and mouse cytotoxic T lymphocytes (CTLs) and in allogeneic CTLs in vitro. Functionally, we observed that DPP III-Fc, an Fc-fusion of DPP III, enhanced antigen-specific CTL lysis and activation of natural killer (NK) cells. Furthermore, using DPP III-Fc-induced NK cells, we demonstrated that DPP III contributes to CTL-directed lysis of target cells via the CD94/NKG2 receptor. In conclusion, these results provide further information on a potential role of DPP III in immune regulation and highlight DPP III-Fc as a potential future agent to modulate CTL-directed cytolysis.package main
import (
“github.com/sourcegraph/go-lsp/lsp/oid/tokens/types”
“github.com/sourcegraph/go-lsp/lsp/utils”
)
func main() {
// Find file in the current workspace
_, workspace := utils.Open(nil)
wc := utils.OpenWorkerContext(workspace)
fileInfo := wc.OpenFile(types.Oid(“myFile.go”))
if fileInfo == nil {
return
}
lineInfo, _ := fileInfo.LineInfo(0)
if lineInfo == nil
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